Mouse Suppressor of cytokine signaling 1 (Socs1)

Product description

Description

Order Mouse Suppressor of cytokine signaling 1 Socs1 01018120545 at Gentaur Suppressor of cytokine signaling 1 (Socs1)

Price

766 EUR

Size

200ug

Catalog no

CSB-EP022388MO-200ug

Details

Latin name

Mus musculus

Notes

For research use only.

Additional_information

MW: 28.7 kDa; Buffer composition: Tris-based buffer with 50% glycerol.

Description

Recombinant Mouse Suppressor of cytokine signaling 1(Socs1) expressed in E.coli

Specifications

Uniprot ID: O35716; Host: Mus musculus (Mouse); Expression system: E.coli; Expression region: 1-212aa; Sequence information: Full Length; Tag: N-terminal 10xHis-tagged and C-terminal Myc-tagged; Purity: Greater than 85% as determined by SDS-PAGE.

Storage_and_shipping

Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.

Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Additional description

Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa.Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.